e/Polyglutamylation

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has glosseng: Polyglutamylation is a form of reversible posttranslational modification of glutamate residues seen for example in alpha and beta tubulins, nucleosome assembly proteins NAP1 and NAP2. The Gamma carboxy group of glutamate may form peptide like bond with the Amino group of a free glutamate whose alpha carboxy group can now be extended into a polyglutamate chain. The glutamylation is done by the enzyme glutamylase and removed by deglutamylase.
lexicalizationeng: Polyglutamylation
instance of(noun) any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
protein
Meaning
Japanese
has glossjpn: ポリグルタミル化(ポリグルタミルか、Polyglutamylation)は、タンパク質のグルタミン酸残基への可逆的翻訳後修飾で、例えばα-、β-チューブリン、NAP1(Nucleosome Assembly Proteins-1)、NAP2(Nucleosome Assembly Proteins-2)で見られる。グルタミン酸のγカルボキシ基が別のグルタミン酸のフリーなアミノ基とポリグルタミラーゼによってペプチド結合し、それ以降、αカルボキシ基からポリグルタミン酸鎖が延長されていく 。グルタミル化はグルタミラーゼ、除去は脱グルタミラーゼと呼ばれる酵素によって行われる。
lexicalizationjpn: ポリグルタミル化

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