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has gloss | eng: F-box proteins are proteins containing at least one F-box motif, a protein structural motif of about 50 amino acids that mediates protein-protein interactions. The first identified F-box protein is one of three components of the SCF complex, which mediates ubiquitination of proteins targeted for degradation by the proteasome. The F-box motif interacts directly with the SCF protein Skp1 , and F-box motifs commonly exist in proteins in concert with other protein-protein interaction motifs such as leucine-rich repeats and WD repeats, which are thought to mediate interactions with SCF substrates . |
lexicalization | eng: F-box protein |
instance of | (noun) any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein" protein |
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